{"id":8444,"date":"2026-06-16T14:41:05","date_gmt":"2026-06-16T14:41:05","guid":{"rendered":"https:\/\/www.pezcoller.it\/?page_id=8444"},"modified":"2026-08-26T09:15:51","modified_gmt":"2026-08-26T09:15:51","slug":"pezcoller-foundation-sic-fellowship-winners","status":"publish","type":"page","link":"https:\/\/www.pezcoller.it\/en\/pezcoller-foundation-sic-fellowship-winners\/","title":{"rendered":"Pezcoller Foundation-SIC Fellowship winners"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” width=”100%” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.7″ _module_preset=”default” text_text_color=”#951542″ header_2_font=”Lato|700|||||||” header_2_text_color=”#83004A” header_2_font_size=”30px” hover_enabled=”0″ locked=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

The research carried out by Pezcoller-SIC fellowship recipients<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.27.7″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#83004A” header_3_font_size=”19px” custom_margin=”-13px|||||” hover_enabled=”0″ locked=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

2025-2026 Fellowships<\/h3>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

GABRIELE ANTONARELLI<\/strong> (European Institute of Oncology, Milan)<\/span><\/p>\n

“Identification Of Toxicity Biomarkers To Trastuzumab-Deruxtecan (T-Dxd) In Patients With Advanced Breast Cancer. Tox-Dxd: An Observational, Non-Interventional, Study”<\/em><\/p>\n

His project aims to identify biomarkers capable of predicting<\/span>
adverse events in the treatment of advanced<\/strong><\/span> <\/span>breast cancer <\/strong><\/span>with Trastuzumab-deruxtecan. The research includes a retrospective analysis<\/strong> <\/span>of 112 patients<\/strong>, recently published in ESMO Open, and a<\/span> prospective phase involving the monitoring of 84 patients.<\/strong><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2026\/03\/gabriele-antonarelli.jpg” title_text=”gabriele-antonarelli” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

LUCREZIA CAMICIA<\/strong> (Centro di Riferimento Oncologico, Aviano)<\/span><\/p>\n

“Study the role of Multimerin-2 in shaping tumor vessel stability to control the chemo\/immunotherapy response”<\/span><\/em><\/span><\/p>\n

Multimerin-2 is an extracellular matrix protein essential for blood vessel health<\/strong><\/span>, a key factor in evaluating the efficacy of anticancer therapies<\/strong>. Our study aims to investigate its role as a potential biomarker, with <\/span>the goal of making treatments increasingly effective<\/strong>.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2026\/03\/lucrezia-camicia.jpg” title_text=”lucrezia-camicia” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

MATTIA COLUCCI <\/strong>(Casa Sollievo Sofferenza, S. Giovanni Rotondo)<\/span><\/p>\n

“The functional role of EZH2 inactivation in the pathogenesis of HOXA-overexpressing Tcell acute lymphoblastic leukemia”<\/span><\/em><\/p>\n

The project aims to provide deeper insights into the molecular mechanisms of an aggressive form of childhood leukemia<\/span><\/strong> (ETP-ALL). It investigates how the combination of genetic alterations<\/strong> promotes the disease, with the goal of identifying new therapeutic targets to develop more effective and less toxic treatments <\/strong>for young patients.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2025\/07\/colucci.jpg” title_text=”colucci” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

ANDREA COSTAMAGNA<\/strong> (University of Torino)<\/span><\/p>\n

“Exploring the role of p130Cas in early metastatic pancreatic cancer cells”<\/span><\/em><\/span><\/p>\n

Pa<\/strong>ncreatic ductal adenocarcinoma<\/strong><\/span> is among the most aggressive tumors due to its high metastatic potential. The project investigates how the p130Cas protein, activated by the mutated Kras oncogene, promotes the early dissemination of cancer cells<\/strong> through the PI3K-AKT signaling pathway, identifying potential therapeutic <\/strong>vulnerabilities<\/strong>. <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2026\/03\/andrea-costamagna.jpg” title_text=”andrea-costamagna” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

MARIA VALERIA GIULI <\/strong>(University La Sapienza, Rome)<\/span><\/p>\n

“Boosting synthetic lethality in High-Grade Serous Ovarian Cancer: induction of “BRCAness” via Pin1 inhibition”<\/span><\/em><\/span><\/p>\n

Ovarian cancer<\/span><\/strong> is among the most lethal gynecological malignancies due to its high resistance to therapies. The study of BRCA gene mutations has improved treatments. This research investigates Pin1\u2014an enzyme that regulates the function of many proteins, including BRCA1\u2014as a therapeutic target to enhance treatment efficacy<\/strong>, even in patients without BRCA mutations. <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2026\/03\/maria-valeria-giuli.jpg” title_text=”maria-valeria-giuli” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

TANIA PORCELLI<\/strong> (University of Palermo)<\/span><\/p>\n

“Obesity Prompts a Permissive Microenvironment to Initiating-Tumor Process “<\/span><\/em><\/span><\/p>\n

In the context of breast cancer<\/strong><\/span>, adipose tissue under obese conditions <\/strong>undergoes dysfunctional changes that promote the onset of pre-malignant alterations<\/strong> and tumor progression. Understanding these mechanisms will contribute to the development of novel therapeutic strategies. <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2025\/01\/porcelli-gaetana.jpg” title_text=”porcelli-gaetana” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”-17px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font=”Lato||||||||” text_font_size=”15px” header_3_font=”Lato|600|||||||” header_3_text_color=”#951542″ header_3_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

JESSICA RUZZOLINI<\/strong> (University of Firenze)<\/span><\/p>\n

“Targeting YAP\/TAZ signaling to overcome drug resistance in BRAF(V600E) melanoma cells”<\/span><\/em><\/span><\/p>\n

Melanoma <\/strong><\/span>is a highly aggressive and increasingly widespread form of skin cancer. Identifying new therapeutic targets to counteract drug resistance<\/strong> is essential for developing more effective treatments<\/strong> aimed at the definitive eradication of the disease. <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.pezcoller.it\/wp-content\/uploads\/2026\/03\/jessica-ruzzolini.jpg” title_text=”jessica-ruzzolini” _builder_version=”4.27.6″ _module_preset=”default” width=”58%” max_width=”100%” custom_margin=”-3px|||||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

The research carried out by Pezcoller-SIC fellowship recipients2025-2026 FellowshipsGABRIELE ANTONARELLI (European Institute of Oncology, Milan) “Identification Of Toxicity Biomarkers To Trastuzumab-Deruxtecan (T-Dxd) In Patients With Advanced Breast Cancer. Tox-Dxd: An Observational, Non-Interventional, Study” His project aims to identify biomarkers capable of predictingadverse events in the treatment of advanced breast cancer with Trastuzumab-deruxtecan. The research includes […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"give_campaign_id":0,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","yasr_overall_rating":0,"yasr_post_is_review":"","yasr_auto_insert_disabled":"","yasr_review_type":"","footnotes":""},"folder":[60],"class_list":["post-8444","page","type-page","status-publish","hentry"],"yoast_head":"\nPezcoller Foundation-SIC Fellowship winners - Fondazione Pezcoller<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pezcoller.it\/it\/borsisti-fondazione-pezcoller-sic\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pezcoller Foundation-SIC Fellowship winners - Fondazione Pezcoller\" \/>\n<meta property=\"og:description\" content=\"The research carried out by Pezcoller-SIC fellowship recipients2025-2026 FellowshipsGABRIELE ANTONARELLI (European Institute of Oncology, Milan) "Identification Of Toxicity Biomarkers To Trastuzumab-Deruxtecan (T-Dxd) In Patients With Advanced Breast Cancer. 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